The Definition of Respiratory Protection
Respiratory protection is equipment and program elements used to protect workers from inhaling hazardous airborne substances.
Respiratory protection is equipment and program elements used to protect workers from inhaling hazardous airborne substances.

Equipment and program elements used to protect workers from inhaling hazardous airborne substances — dust, fumes, gases, or vapors — including respirators ranging from simple filtering facepieces to supplied-air systems. OSHA's Respiratory Protection Standard (29 CFR 1910.134) governs its use.
A painter working with solvent-based coatings in a poorly ventilated booth wears a half-face respirator with organic vapor cartridges as part of a respiratory protection program that also requires annual fit testing and medical evaluation.
It's required when engineering and administrative controls aren't sufficient to keep airborne contaminant exposure below applicable limits, or in situations where those controls aren't feasible. A written respiratory protection program is required for any workplace where respirator use is mandatory.
A filtering facepiece (like an N95) filters contaminants from ambient air the wearer breathes, while a supplied-air respirator delivers clean air from an outside source, such as a compressed air line or self-contained tank. Supplied-air systems are used for higher-hazard environments, including oxygen-deficient or IDLH atmospheres.
Wearing a respirator places physiological demands on the body — added breathing resistance and, in some cases, weight — that can be dangerous for workers with certain heart or lung conditions. OSHA requires medical evaluation to confirm a worker can safely wear the assigned respirator before fit testing occurs.
A qualitative fit test relies on the wearer detecting a test agent (like a bitter or sweet taste) to confirm a seal, while a quantitative fit test uses instrumentation to measure the actual fit factor numerically. Quantitative testing is required for tighter-fitting respirators used in higher-hazard atmospheres.
Yes, significantly. Facial hair that crosses the sealing surface of a tight-fitting respirator can prevent an adequate seal, which is why OSHA prohibits facial hair in that area for workers required to wear tight-fitting respirators, regardless of fit test results.